The section, EDAIC Multiple Choice Question and answer, covers a different topic each day with the intent that candidates can prepare one small topic each day, making steady progress in their exam preparation.
Question: Identify the agents known to cause pulmonary fibrosis
- Methotrexate
- Paraquat
- Dexamethasone
- Bleomycin
- Propanolol
Answers:
- true
- true
- false
- true
- true
ANAESTHETIC IMPLICATIONS OF THE CARDIAC IMPLANTABLE ELECTRONIC DEVICES (CIEDs)
Explanation:
Some of the commoner medication types that are known to carry the risk of pulmonary fibrosis include certain:
- Chemotherapy drugs:
- Cytotoxic antibiotics (e.g. bleomycin, mitomycin-C, and doxorubicin)
- nitrosoureas (e.g. lomustine)
- alkylating agents (e.g. cyclophosphamide, ifosfamide, melphalan, chlorambucil)
- anti-metabolites (e.g. methotrexate, azathioprine, cytarabine, fludarabine)
- plant alkaloids (e.g. vincristine, vinblastine, etoposide)
- biological response modifiers (e.g. GM-CSF, interleukin-2, interferon, BCG)
- others: taxol
* Bleomycin is often used to treat germ cell tumours and Hodgkin’s disease. The major limitation of bleomycin therapy is the potential for subacute pulmonary damage that can progress to life-threatening pulmonary fibrosis. Pulmonary toxicity occurs in 6–10% of patients and can be fatal
2. Drugs for heart conditions: amiodarone, propanolol
3. Long term exposure to dust (silica, asbestos, grain dust, bird droppings) and irritating fumes. Farmers, mine workers, chronic smokers, stone cutters/polishers and metal workers may be at an increased risk of pul fibrosis
*Paraquat is a non-selective bipyridyl pesticide and is one of the leading causes of death from intoxication in many parts of Asia and America.
4. Antibiotics, such as nitrofurantoin and sulfa drugs.
5. Radiation therapy
Mock-tests for EDAIC multiple choice questions (part-1) are now available for your practice and making you familiar with the exam pattern, and complexity. The practice will come in handy when the final exam FINALLY arrives. The tests have been launched keeping in mind the much needed last-minute practice and revision required for September 2021 exam.
You can take the test and gauge your preparation level. Detailed explanations are also available for desiring candidates. The exam result will be emailed to you with or without explanations as per your result.
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‘EDAIC Multiple Choice Question and answer’ covers a different topic each day with the intent that candidates can prepare one small topic each day, making steady progress in their exam preparation.
