EDAIC Multiple Choice Question and answer. FREE UPLOADS BY WWW.TARGETEDAIC.COM (72)

The section, EDAIC Multiple Choice Question and answer, covers a different topic each day with the intent that candidates can prepare one small topic each day, making steady progress in their exam preparation.

Question: Thiopental

1. is an analgesic in low doses.
2. its sodium salt is highly water-soluble
3. causes a decrease in central nervous system (CNS) carbon dioxide production
4. forms insoluble crystals when injected intra-arterially.
5. Acidotic patients need less thiopental for the same effect

Answers:

1. 1. false
   2. false
   3. true
   4. true
   5. true

Explanation:

• Sodium thiopentone is highly lipophilic
• At very low doses thiopental is antanalgesic
• Thiopental reduces brain activity and therefore decreases oxygen consumption and CO2 production.
• Insoluble crystals form in both venous and arterial systems; however, the collateral venous supply dilutes these crystals. Crystal formation in the arterial system can lead to distal infarction.
• Thiopental is a weak acid; with a decrease in pH there is an increase in free unionised drug and therefore it has a greater response.

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‘EDAIC Multiple Choice Question and answer’ covers a different topic each day with the intent that candidates can prepare one small topic each day, making steady progress in their exam preparation.