The section, EDAIC MCQ with an explanation, covers a different topic each day with the intent that candidates can prepare one small topic each day, making steady progress in their exam preparation.
Question: Identify the correct statements regarding xenon:
- It is a naturally occurring gas.
- Approx 20% of xenon is metabolized.
- MAC: 2.
- It is relatively soluble as compared to other inhaled anaesthetic agents.
- It causes a significant dose-dependent reduction in arterial blood pressure.
Answers:
- false
- false
- false
- false
- false
Explanation:
Xenon
- It is a naturally occurring odourless, inert gas that has been used as an inhalational anaesthetic.
- It is inert and does not combine with other molecules, and is completely eliminated without any metabolism.
- It is relatively insoluble (blood: gas partition coefficient 0.115), reaching equilibrium with the tissues quickly and providing a rapid onset and emergence.
- MAC: 0.71.
- Mechanism of action: Antagonism o the NMDA receptors in the central nervous system.
- It is expensive and has a limited supplyas it cannot be manufactured and has to be extracted from the air.
- It has minimal cardiorespiratory effects, and blood pressure, contractility, heart rate, and systemic vascular resistance are all essentially unchanged.
- It does cause a slight increase in airway pressure, an effect that is due to its increased viscosity compared to oxygen and not due to an increase in bronchial tone.
- It has a promising neuroprotective agent.
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‘EDAIC MCQ with an explanation’ covers a different topic each day with the intent that candidates can prepare one small topic each day, making steady progress in their exam preparation.
